Analysis of urinary protein patterns for diabetes by protein chip
- VernacularTitle:糖尿病患者尿液蛋白质质谱分析
- Author:
Lixia ZOU
;
Wei GU
;
Yiding CHEN
- Publication Type:Journal Article
- Keywords:
Diabetic nephropathies;
Protein chip;
Albumin;
Artificial neural network
- From:
Chinese Journal of Endocrinology and Metabolism
2008;24(2):185-187
- CountryChina
- Language:Chinese
-
Abstract:
Urine samples from diabetic and healthy subjects were detected by H4 protein chip and surface-enhanced laser desorption/ionization time of flight mass spectrometry (SELDI-TOF-MS).Some significantly differential proteins between diabetic and controls were found.Four top-scored protein peaks were finally selected as the potential "fingerprints" for detection of early diabetic nephropathy by artificial neural network (ANN) classifier.
