A multi-centers clinical study of difierent treatment outcomes of 332 patients with multiple myeloma
- VernacularTitle:多发性骨髓瘤患者332例疗效分析
- Author:
Kai XUE
;
Lugui QIU
;
Ting LIU
;
Jian HOU
;
Xiaojun HUANG
;
Jun MA
;
Xiequn CHEN
;
Li YU
;
Jie JIN
;
Depei WU
;
Yongji WU
;
Fanyi MENG
;
Jianyong LI
;
Wenming CHEN
;
Chun WANG
;
Jianmin WANG
;
Zilun HUANG
;
Ping ZOU
;
Shifeng LOU
;
Jian OUYANG
;
Fan ZHOU
;
Xin DU
;
Zhixiang SHEN
- Publication Type:Journal Article
- Keywords: Multiple myeloma; Treatment outcome; Muhicenter studies
- From: Chinese Journal of Internal Medicine 2008;47(2):98-101
- CountryChina
- Language:Chinese
- Abstract: Objective To describe the demographic and clinical characteristics of patients with the diagnosis of multiple myeloma(MM)and to analyse the outcome of difierent regimens for the treatment of MM.Methods The study reviewed 332 MM cases diagnosed within the period from January 1,2002 to December 31,2002.These patients were tracked via their records to a total period of three years.Results First-line treatment:Totally 332 patients were included,among them 325(97.9%)patients received chemotherapy and 7(2.1%)patients received stem cell transplantation(SCT);Second-line treatment:197 patients were included,among them 190(96.5%)patients received chemotherapy and 7(3.6%)patients received SCT;Third-line treatment:92 patients were included,among them 88(95.7%)patients received chemotherapy and 4(4.4%)patients received SCT.Major adverse effects were follows:severe infection 19.3%,severe anaemia 19.3%,phlebothrombosis 1.2%,thrombocytopenia 16.9%,fever associated with neutropenia 18.1%.Conclusions Some curative effects can be achieved by using traditional treatment plans to treat patients suffering from MM,but new methods are expected to improve the prognosis.