Application of drug-loaded nanoparticles in tissue engineering
- VernacularTitle:载药纳米粒子在组织工程领域的应用
- Author:
Renan CHANG
;
Zhong CHEN
- Publication Type:Journal Article
- Keywords:
Nanotechnology;
Tissue engineering;
Growth factors;
Gene sequence
- From:
International Journal of Biomedical Engineering
2008;31(2):97-101
- CountryChina
- Language:Chinese
-
Abstract:
Drag-loaded nanoparticle is a new delivery cartier of drug and biomacromoleculc,which have many fortes such as target ability,permeability,controlled release ability and function of promoting cell differentiation.Polypeptide combined nanoparticles can deliver drugs to the targeted tissues by conjugating with specific ligands.Growth factor combined nanoparticles may have better curative effect by maintaining the activity of the growth factors longer.Nanoparticles can effectively deliver genes to the cells in the injured tissue for the enhancemem of the specific function of the cells.Three dimension nanometer fibrous structure combined with nanoparticle based drug delivery could significantly promote the growth of the cell.Magnetic nanoparticles are widely used for the targeted delivery of drugs or genes and separation of biomolecules.Drug loaded nanoparticles have been increasinsly used in tissue enginerring which have shown a tremendous potential.In the present paper,we reviewed the application of drug-loaded nanoparticles in the field of tissue engineering.
