Advances of EC promoting vascularization in tissue-engineered bone
- VernacularTitle:血管内皮细胞促进组织工程骨血管化的研究进展
- Author:
Yi CHEN
;
Danping LIU
- Publication Type:Journal Article
- Keywords:
Tissue engineering bone;
Angiogenesis;
Vasculogenesis;
Vascular endothelial cell
- From:
International Journal of Biomedical Engineering
2008;31(2):119-122
- CountryChina
- Language:Chinese
-
Abstract:
The vaseularization of tissue-engineered bone is the key problem which the development and employment of large sized tissue-engineered bone.The vascular endothelial cell has a great effect on promoting vascularization in tissue-engineered bone.Vascularizations fall into two modes of vaseulogenesis and angiogenesis according to differences in source of endothelial cells.Co-culture of osteoblasts and vascular endothelial cells has better result than single culture of each kind of cells.Different ways of improving the vascularization,such as searching for new source of vascular endothelial cell,co-culture and in vivo experiment are investigated to meet the challenge of bone tissue engineering.
