Correlation of apolipoprotein M with severity of coronary artery stenosis in patients with coronary heart disease
- VernacularTitle:载脂蛋白M与冠心病患者冠状动脉病变的关系
- Author:
Jianhui SUN
;
Jiangtao BAI
;
Haiyan KE
;
Yaping LIU
;
Xiaoyu YANG
;
Meizhen SHEN
;
Guanghua LUO
- Publication Type:Journal Article
- Keywords:
Apolipoprotein M;
Coronary disease
- From:
Chinese Journal of General Practitioners
2008;7(3):187-188
- CountryChina
- Language:Chinese
-
Abstract:
One hundred and thirty seven pafients diagnosed by coronary angiography were recruited in the study and divided into coronary heart disease group(CAD)and control group.Relationship between serum apolipoprotein M levels and the severity of stenosis of coronary arteries was analyzed.In covariate analysis,serum apolipoprotein M levels were significantly lower in CAD group than those in control group adjusted for sex,age,body mass index(BMI)(P＜0.05).By stepwise muhiple regression,serum levels of apolipoprotein M were correlated positively with BMI(r=0.65,P＜0.01),and correlated negatively with total cholesterol(TC)(r=-0.53,P＜0.01)and low density lipoproteins(LDL-C)(r=-0.42,P＜0.01).Serum levels of apolipoprotein M were correlated negatively with the score of coronary stenosis(r=-0.62,P＜0.01).The results suggest that apolipoprotein M might be related to the development of coronary artery disease.
