Association between serum amyloid A and intima-media thickness of common carotid artery in patients with type 2 diabetes
- VernacularTitle:2型糖尿病血清淀粉样蛋白A水平与颈总动脉内中膜厚度相关
- Author:
Yu YANG
;
Jianling DU
;
Xiujuan ZHANG
;
Ran BAI
;
Ying BA
;
Qian XING
;
Lipeng SUN
;
Guohua SUN
;
Changchen LI
- Publication Type:Journal Article
- Keywords:
Serum amyloid A;
Diabetes mellitus;
type 2;
Intima-media thickness
- From:
Chinese Journal of Endocrinology and Metabolism
2008;24(2):188-189
- CountryChina
- Language:Chinese
-
Abstract:
A total of 169 patients with short-duration type 2 diabetic mellitus (DM) were divided into atherosclerosis (AS) group and non-AS group according to the intima-media thickness (IMT) of three conducting arteries.The level of serum amyloid A (SAA) was assayed by ELISA.The results showed that SAA level of type 2 DM patients increased significantly, patients in AS group showed higher SAA level than that in non-AS group, and SAA level was positively correlated with age, body mass index, waist hip ratio and IMT of common carotid artery.Age, C-reactive protein and SAA level are the major risk factors for IMT of common carotid artery.