Voltage-dependent calcium channel(VDCC)LTP and N-methyl-D-aspartate(NMDA)receptor channel LTP
- VernacularTitle:LTP的钙离子通道机制:VDCC LTP和NMDA LTP
- Author:
Wenjuan TIAN
;
Xin TIAN
- Publication Type:Journal Article
- Keywords:
Long-term potentiation;
Memory;
N-methyl-D-aspartate receptor channel;
Voltagedependent calcium channel;
Low frequency stimulation
- From:
International Journal of Biomedical Engineering
2008;31(2):74-77
- CountryChina
- Language:Chinese
-
Abstract:
Long-term potentiation(LTP)is a typical model of synaptic plasticity which has great relationship with learning and memory mechanisms:The induction of LTP depends on the activation of the calcium channels and LTPs generated by calcium ions influx through different channels play different roles in memory.This paper reviews the progress of the research on LTPs induced by activations of N-methyl-D-aspanate receptor(NMDAR)channels and voltage-dependent calcium channels(VDCC).Finally,it gives an example of new forms of low frequency stimulation for induction of LTP.
