Combined vaccination with immunoglobulin in prevention of vertical transmission of HBV from father to baby
- VernacularTitle:联合免疫预防乙型肝炎病毒父婴传播的初步研究
- Author:
Liangbin XIA
;
Lei JIANG
;
Aibin LI
;
Jing YANG
;
Wangming XU
- Publication Type:Journal Article
- Keywords:
Hepatitis B virus;
Vaccination
- From:
Chinese Journal of General Practitioners
2008;7(3):181-182
- CountryChina
- Language:Chinese
-
Abstract:
Four hundred and five pregnant women whose husbands had positive HBeAg,HBsAg and anti HBc were recruited in the study.Among them.218 women with positive HBsAb were completely randomized into group A and group B,while 187 cases with negative HBsAb formed group C.Women in group A and group C were injected with hepatitis B immunoglobulin(HBIG)before delivery.All newborn babies in 3 groups received routine HCV vaccination.in addition babies in group A and group C also received HBIG iniection within 24 h after birth.The HBV infeetion rate of newborns was 12.1%in group A,12.8%in group B and 23.0%in group C respectively.
