The diagnostic value of neutrophilic alkaline phosphatase activity detection in systemic lupus erythematosus
- VernacularTitle:中性粒细胞碱性磷酸酶活性测定对系统性红斑狼疮的诊断价值
- Author:
Mingli SUN
;
Meipu CHEN
;
Shixue LI
;
Jie SONG
;
Yunzhi LI
- Publication Type:Journal Article
- Keywords:
Alkaline phosphatase;
Lupus erythematosus,systemic
- From:
Chinese Journal of Primary Medicine and Pharmacy
2008;15(3):394-395
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the diagnostic value of NAP activity detection in SLE.Methods Technique of AS-BI was used to NAP staining of peripheral blood smear in patients with newly-diagnosed SLE(30 cases)and normal healthy women(30 cases),to observe positive rate and positive score of NAP.Results The positive rate was(22.1±8.8)% in group SLE,(56.8±9.4)% in group normal;The positive score was(22.2±8.9)in group SLE,(58.2±9.8)in group normal.The positive rate and positive score were much lower in patients with SLE comparing with those in group normal.Differences were statistically significant(P＜0.01).Conclusions The detection of NAP is useful in the patients with newly-diagnosed SLE,but we must go on researching the pathogenesis of NAP activity decreased in SLE.
