Multi-slice spiral CT perfusion imaging of chronic obstructive pulmonary disease
- VernacularTitle:多层螺旋CT灌注成像对慢性阻塞性肺疾病的诊断价值
- Author:
Yanhui SHAO
;
Nong QIAN
;
Yuejun XUE
;
Yihong DAI
- Publication Type:Journal Article
- Keywords:
Lung diseases,obstructive;
Tomography,X-ray computed;
Perfusion
- From:
Chinese Journal of Radiology
2008;(3):281-284
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the diagnostic value of multi-slice spiral CT(MSCT)perfusion imaging in chronic obstructive pulmonary disease(COPD).Methods Twenty COPD patients and20 volunteers underwent 8-row detector spiral CT(MSCT)perfusion imaging using cine scan mode with5 mm slice thickness.0.5 s rotation time and a total scan time of 45 s with 5 s intervals.60 ml contrast agent(300 mg I/ml)were administered at a rate of 4 ml/s from the forearm superficial vein.The imaging data were transferred to a workstation.A time-density curve and pseudo-color map were generated automatically with GE CT perfusion 3 software,the blood flow(BF),blood volume(BV),mean transit time(MTr)and permeability surface(PS)were measured.Results Time-density curve was flatter and the peak of the curve was obviously lower in COPD patients than the volunteers.The BF.BV.PS in COPD volunteers was(10.58 ±4.85)s and(4.50 ±1.71)s respectively.The BF,BV and PS in COPD patients Was lower than the volunteers,the MTY was higher(P＜0.01).Conclusion MSCT perfusion imaging is helpful for the diagnosis of COPD.
