Combination of 308 nm excimer laser with topical pimecrolimus cream for vitiligo in childhood
- VernacularTitle:308 nm准分子激光联合吡美莫司乳膏治疗儿童白癜风的疗效观察
- Author:
Xiaoyan HUANG
;
Huilan YANG
;
Jianyong FAN
;
Xuemei LI
- Publication Type:Journal Article
- Keywords:
Excimer laser;
Vitiligo;
Pimecrolimus
- From:
Chinese Journal of Dermatology
2008;41(4):220-222
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess the efficacy and safety of 308 nm excimer laser plus topical pimeevaluated after 15 and 30 times of laser therapy respectively.ResultsExcept for one patient,all patients were able to be evaluated for effiicacy.After 30 times of laser therapy,the response and excellent response rates were 89.6%and 77.1%respectively,in group A,5.0%and 52.1%respectively in group B;both rates were significantly higher in group A than in group B(both P<0.05).Also,a highler repigmentation rate was obtained in facial lesions in group A compared with group B.Conclusions The 308 nm excimer laser is safe,erective and well-tolerated for vitiligo in childhood,and the combination with topical imecrolimus cream may improve its efficacy in facial vitiligo.