Effect of Repeated Transient Ischemic Attacks on Cumulative Injury of Cognitive Function:A Clinical study
- VernacularTitle:反复短暂性脑缺血发作对认知功能累积性损害的临床研究
- Author:
Chuan HE
;
Aiqin WU
- Publication Type:Journal Article
- Keywords:
transient ischemic attack;
cognitive impairment
- From:
International Journal of Cerebrovascular Diseases
2008;16(3):173-176
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the effect of repeated transient ischemic attacks(TIAs)on cumulative injury of cognitive function.Methods:The cognitive condition of 42 patients with repeated TIAs were assessed after each TIA using the event related potential,modified version of Wisconsin card sorting test,trail making test,digit span task,and verbal fluency test.The cognitive condition was compared and analyzed after different attack times.Results:There were significant differences among the cognitive condition after different attack times,latency and amplitude of P300,and detection rate of mild cognitive impairment.With the increase of the attack times,cognitive impairment aggravated gradually,and the detection rate of mild cognitive impairment increased gradually.Conclusions:Repeated TIAs have cumulative injury on cognitive function.The prevention and treatment of cerebral ischemia may become an important approach in decreasing cognitive impairment.