Case report and literature review of epithelioid trophoblastic tumor
- VernacularTitle:上皮样滋养细胞肿瘤六例临床分析
- Author:
Xiaodong CHENG
;
Weiguo LU
;
Xiaoyun WAN
;
Xiaoduan CHEN
;
Xing XIE
- Publication Type:Journal Article
- Keywords:
Trophoblastic neoplasms;
Uterine neoplasms;
Prognosis
- From:
Chinese Journal of Obstetrics and Gynecology
2008;43(4):281-285
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical characteristics of epithelioid trophoblastic tumor (ETT).Methods Six cases of ETT treated in Women's Hospital,School of Medicine,Zhejiang University from 2005 to 2007 were retrospectively analyzed,together with a literature review.Results Six cases of ETT were diagnosed pathologically after surgery.The age of patients ranged from 27 to 46 years.The most common presentation was abnormal vaginal bleeding(5/6).The preceding gestational events were hydatidiform mole in 1 case,abortion in 2 cases,and term delivery in 3 cases.The interval between the preceding gestation and the diagnosis of ETT ranged from 15-48 months.The serum human chorionic gonadotropin(hCG)level was 46-121 147 IU/L.Four cases presented with metastasis,including lung metastasis in all of the 4 cases,liver metastasis in 1 case,and pancreas metastasis in another 1 case.The main therapies were surgery combined with chemotherapy.All of the 6 cases received total abdominal hysterectomy.and 1 case also had lung lobectomy.One ease had a recurrence but refused any treatment again,and was lost to follow up;the therapy of 1 case unfinished;another 4 cases were without evidence of disease 9 to 19 months after surgery.Condusions The confirmation of ETF diagnosis is difficult before surgery.Surgical management is mostly recommended in ETT. The role of chemotherapy in ETT is not clear yet.
