Effects of Fosinopril vs Amlodipine on brachial ankle pulse wave velocity and pulse pressure in patients of primary hypertension
- VernacularTitle:福辛普利和苯磺酸氨氯地平对原发性高血压患者大动脉僵硬度和脉压的影响
- Author:
Xiaping XIANG
;
Dayi HU
;
Hanyin YUAN
;
Xinhui NING
;
Yu LIU
;
Wenjun WANG
- Publication Type:Journal Article
- Keywords:
Antihypertensive agents;
Pulse wave velocity
- From:
Chinese Journal of General Practitioners
2008;7(4):268-270
- CountryChina
- Language:Chinese
-
Abstract:
A total of 560 patients with primary hypertension were divided into two groups.Of them,260 were treated with Fosinopril(10～20 mg once daily),and the other 300 were treated with Amlodipine (5～10 mg once daily).The treatment lasted for 12 months in both groups.The levels of blood pressure (BP)、braehial ankle pulse wave velocity(baPWV)and pulse pressure(PP)were examined at baseline,6 month and 12 month with automatic analysis system of arteriosclerosis.BP in Amlodipine group(132/76 mm Hg)decreased more significantly than Fosinopril group(136/85 mm Hg),but Fosinopril group showed more remarkable changes in baPWV(1310 cm/s)and PP(52 mm Hg)than Amlodipine group(1400 cm/s and 56 mm Hg).
