Resistance to fluoroquinolones and amikacin in escherichia coli isolates
- VernacularTitle:大肠埃希菌对氟喹诺酮类和阿米卡星的耐药性分析
- Author:
Xin AN
;
Zizhong XIONG
;
Hongxia CAO
- Publication Type:Journal Article
- Keywords:
Escherichia;
Ciprofloxacin;
Ofloxain;
Amikacin;
Drug resistance,bacteral
- From:
Chinese Journal of Primary Medicine and Pharmacy
2008;15(4):540-541
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the resistance to fluoroquinolones and amikacin in escherichia coti isolates. Methods ESBLs-producers were detected by CLSI phenotypic confirmatory test and susceptibilities were tested by agar dilution method. Results 33. 8% of 361 isolates were ESBLs-producers. The resistant rate of ciprofloxacin,levofloxacin, amikaxin was 93.4%, 90.9%, 13.1% in ESBLs-produeers, and that was 69.5%,68.6 %, 19.7 % in non-ESBLs-producers, respectively. Conclusion Amikaxin is active against most escherichia coli isolates; those isolates are highly resistant to fluoroquinolones, especially, in ESBLs-producers.
