The clinical effect of leukocyte filter preventing nonhemolytic febrile transfusion reactions
- VernacularTitle:白细胞过滤器预防非溶血性发热性输血反应的效果
- Author:
Xisui CHEN
;
Yuanshan CHENG
;
Yuansheng LIU
;
Huijun LI
- Publication Type:Journal Article
- Keywords:
Micropore filters;
Erythrocyte transfusion;
Antigen-Antibody reactions
- From:
Chinese Journal of Primary Medicine and Pharmacy
2008;15(4):584-585
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical effect of using leukocyte filter to prevent nonhemolytic febrile transfusion reactions(NHFTR) in hematologic patients who were trarisfused erythrocyte suspension. Methods Select 720 inpatients need erythrocyte transfusion and have transfusion records. The patients were randomly divided into investigation group and control group. We made a routine examination and recorded the patients' body temperature, heart rate, blood pressure, respiration rate and transfusion adverse reaction before and after erythrocyte suspeusion transfusion. Results Before blood transfusion, the body temperature of patients between two groups were normal, but after blood transfusion, there were 35 patients with NHFTR in the control group, while only 5 cases in the investigation group which used leucocyte filter, the difference between two groups is significant( P＜0.01 ). The change of the patients' body temperature were compared between two groups before and after transfusion, the changes in the control group was significantly higher than the investigation group( P＜0.01 ). Compared the changes of serum total bilirubin level in all patients before and after transfusion,there was no difference in both groups. The incidence of NHFTR increased with increasing of the transfusion times, but compared with the investigation group,the incidence of the control group was higher significantly(P＜0.01 ). Conclusion Leukocyte filter can prevent the occurring of NHFTR efficiently, enhance the quality of transfusion,guarantee the blood transfusion safety.
