Subject application of new pre-operation auxiliary chemotherapy in treating cervical carcinoma

VernacularTitle:宫颈癌术前新辅助化疗疗效观察
Author: Yanbing LI ; Lili HAN ; Juan LI
Publication Type:Journal Article
Keywords: Uterine cervical neoplasms; Chemotherapy,adjuvant
From: Chinese Journal of Primary Medicine and Pharmacy 2008;15(4):609-610
CountryChina
Language:Chinese
Abstract: Objective To explore the application value of new pre-operation auxiliary chemotherapy(NACT)in treating cervical carcinoma. Methods Two periods of chemotherapy were conducted on 53 cervical carcinoma patients;the chemotherapy projects were PVB and BIP;operation was made two weeks afterwards. Results The total effective rate of NACT was 77.4% ,26.4% of which was complete remission;50.9% of which was partial remission;local carcinoma bulk decreased significantly; the post-operation pathology indicated that there was 3.8% of uterus infiltration and 7.1% of pelvic cavity lymph node metastasis. Those patients received chemotherapy after the operation,all patients were followed up. Conclusion NACT is safe and effective for the pre-operation treatment of cervical carcinoma,which can reduce the carcinoma bulk and increase the successful rate of the operation.