The significance of cancer stem cells in the diagnosis and treatment of malignant tumor
- VernacularTitle:肿瘤干细胞对恶性肿瘤诊治的意义
- Author:
Liyu JIANG
;
Xiaoli KONG
;
Jingzhong SUN
- Publication Type:Journal Article
- Keywords:
tumor;
cancer stem cells;
stem cells
- From:
International Journal of Surgery
2008;35(5):346-349
- CountryChina
- Language:Chinese
-
Abstract:
Malignant tumors still threatens the human's health seriously. Metastasis and recurrence lead to the failure of treatment, and multidrug resistance adds the difficulty of therapy of to malignant tumors. But the mechanism is yet unclear. Nowadays, it is found that there's a small group of cells with selfrenewal and indefinite potency in the tumors, and they are the sources of metastasis and recurrence. This small group of cells is called cancer stem cells. Subsequently, the cancer stem ceils were separated and determined from hematological system tumor and solid tumor respectively. The cognitions for metastasis and recurrence and muhidrug resistance of malignant tumor have changed with proposal and verification of the cancer stem cell theory, which provides a new clue to the treatment of tumor and prevention for the metastasis and recurrence.
