Immune mechanisms of obliterative bronchiolitis following lung transplantation
- VernacularTitle:肺移植闭塞性细支气管炎免疫机制研究进展
- Author:
Guangsuo WANG
;
Zheng WANG
;
Zongquan SUN
- Publication Type:Journal Article
- Keywords:
lung transplantation;
obliterative bronchiolitis;
chronic rejection;
immune mechanisms
- From:
International Journal of Surgery
2008;35(5):349-352
- CountryChina
- Language:Chinese
-
Abstract:
Chronic rejection remains the leading cause of chronic allograft dysfunction and late mortality after lung transplantation. Adaptive immune system and its cellular-based rejection has been the focus in the development of obliterative bronchiolitis. Recent research has identified that humoral immunity, autoimmunity, and innate immunity also contribute to obliterative bronchiolitis. This paper presents an updated review of the immune mechanisms for obliterative bronchiolitis following lung transplantation.
