Comparison of vascular complications between adults latent autoimmune diabetes and type 2 diabetes
- VernacularTitle:成人隐匿性自身免疫糖尿病与2型糖尿病的血管并发症比较
- Author:
Xiaohua WANG
;
Zhiguang ZHOU
;
Xia LI
;
Hongguang HUANG
;
Changluo LI
;
Jian LIN
;
Lin YANG
- Publication Type:Journal Article
- Keywords:
Latent autoimmune diabetes in adults;
Type 2 diabetes;
Vascular disease;
Glutamate decarboxylase antibody
- From:
Clinical Medicine of China
2008;24(5):422-424
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the prevalence of microvascular and macrovascular complications between adult latent autoimmune diabetes(LADA)and type 2 diabetic subjects.Methods A cross-sectional study was performed in 203 LADA(GADA positive)and 203 T2DM(GADA negative)subjects matched with age,gender and duration as well as family history of diabetes.Parameters of microvascular(albuminuria、eyeground microscopy or fundus fluorescence photography,electromyogram)and macrovascular complications(electrocardiogram,blood pressure,blood lipid,body mass index)as well as blood sugar were compared.Results ①Microvascular complications:Compared with T2DM,LADA cases showed higher prevalence of diabetic nephropathy(39.9%vs.28.6%,P＜0.05)and similar prevalence in diabetic neuropathy and retinopathy(P＞0.05).②Macrovascular complications:LADA cases presented lower prevalence of hypertension(38.9%vs.55.7%,P＜0.01),lower prevalence of metabolic syndrome (33.0%vs.45.3%,P＜0.01＝,but similar orevalence of coronarv heart disease (CHD) and erebral infarction(CVD)(P＞0.05).Conclusion LADA patients present less metabolic syndrome,hypertension and more diabetic nephropathy compared with T2DM.
