The use of the immunosuppressives for the patients with HCV after renal transplantation
- VernacularTitle:丙型肝炎病毒RNA阳性的肾移植受者免疫抑制剂的应用
- Author:
Fukang SUN
;
Jianyu LING
;
Yu ZHU
- Publication Type:Journal Article
- Keywords:
Kidney transplantation;
Hepatitis C;
Immunosuppressive agents;
Liver function tests
- From:
Chinese Journal of Organ Transplantation
2000;21(3):151-152
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the use of immunosuppressives for the patients with virus C hepatitis(HCV)after renal transplantation.Methods Twenty-five cases of HCV-RNA(+)and 30 cases of HCV-RNA(-)as control group were analyzed.All patients were divided into the Aza group(n=12),MMF group(n=8)and MP(MMF+Pred)group(n=5).Results Eight casGS revealed abnormal liver function in the Aza group and 2 in MMF group.After stopping the use of CsA and Aza,the liver function all revealed good outcome in the MP group.During one week 30 cases of HCV-RNA(-)recovered due to the readjustment of the dosage of immunosupprexsives(CsA,Aza)in the control group.Conclnsions The therapy of MMF+CsA+Pred is necessary for the patients with HCV-RNA(+)and the function of the renal and liver can be stabilized by MMF.