Expression of ICAM-1 and VCAM-1 in human chronic renal allograft rejection
- VernacularTitle:细胞间粘附分子-1和血管细胞粘附分子-1在慢性排斥反应中的表达
- Author:
Xiaoming PAN
;
Yong CHEN
;
Junping XING
- Publication Type:Journal Article
- Keywords:
Kidney/transplantation Rejection ICAM-1 VCAM-1
- From:
Chinese Journal of Organ Transplantation
1998;19(4):217-219
- CountryChina
- Language:Chinese
-
Abstract:
To study the mechanism of human chronic renal allograft rejection, kidney tissues were taken from 16 patients with chronic renal allograft rejection and from 5 healthy subjects, and underwent the frazed section staining for ICAM-1 and VCAM-1 to anti-ICAM-1 and anti-VCAM-1 respectively by using immunohistochemistry(ABC).The results showed that there were differ-ent distribution of ICAM-1 and VCAM-1 expression in nomal kidney and renal allograft during chronic rejection.It was suggested that ICAM-1 and VCAM-1 might play an important role in the pathogenesis of human chronic renal allograft rejection.
