Two Cases of Adenocarcinoma Arising from Short Segment Barrett's Esophagus.
- Author:
Young Kul JUNG
1
;
Jong Jae PARK
;
Jeong Han KIM
;
Sang Kyun YU
;
Ji Yeon LEE
;
Ik YOON
;
Ki Ho PARK
;
Jin Yong KIM
;
Jae Seon KIM
;
Young Tae BAK
;
Woon Yong JEONG
;
Chul Hwan KIM
;
Chang Hong LEE
Author Information
1. Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea. gi7pjj@yahoo.co.kr
- Publication Type:Case Report
- Keywords:
Esophagus;
Adenocarcinoma;
Short segment Barrett's esophagus;
Cytokeratin 7/20
- MeSH:
Adenocarcinoma*;
Barrett Esophagus*;
Cardia;
Diagnosis;
Endoscopy;
Epithelium;
Esophagogastric Junction;
Esophagus;
Metaplasia;
Mucous Membrane
- From:Korean Journal of Gastrointestinal Endoscopy
2004;28(1):18-24
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Barrett's esophagus is considered as a premalignant condition in which columnar epithelium replaces the normal esophageal squamous epithelium. The diagnosis of Barrett's esophagus is based on the endoscopic finding of columnar epithelium lining the distal esophagus and histologic confirmation of the presence of specialized intestinal metaplasia. According to the extent of the metaplastic lining from the esophagogastric junction, Barrett's esophagus has been divided into long-segment (> or =3 cm in length) and short-segment (<3 cm in length). Long-segment Barrett's esophagus can be easily identified at endoscopy, but it is difficult to separate short-segment Barrett's esophagus from intestinal metaplasia of cardia. It has been reported that Barrett's CK 7/20 pattern is an objective marker of Barrett's mucosa, and can differentiate Barrett's mucosa from gastric intestinal metaplasia. We report here two cases of adenocarcinoma of esophagus arising from short-segment Barrett's esophagus, diagnosed by endoscopic and histologic findngs, and treated by endoscopic mucosal resection.
