Preparation and Quality Control of FU FANG QIN KUN Cream
- VernacularTitle:复方芩醌乳膏的制备与质量控制
- Author:
Baoyuan LI
;
Yisheng LIU
;
Yongde ZHAO
;
Hong JIANG
;
Yu WANG
- Publication Type:Journal Article
- Keywords:
Baicalin;
Hydroquinone;
FU FANG QIN KUN Cream;
HPLC
- From:
International Journal of Traditional Chinese Medicine
2008;30(3):191-192
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the methods of preparation and quality control for FU FANG QIN KUN Cream. Methods Baicalin, hydroquinone and vitamin E were serving as main raw material to produce O / W cream by adding suitable emulsifier, HPLC method was used to determine content of baicalin in the cream. Results FU FANG QIN KUN Cream is stable without irritation. The assay method was rapid and accurate. When the dosage of Baicalin was controlled in 0.25μg to 2.5 μg, the sample volume and absorption area percentile showed a good linear relationship. The average recovery was 98.9% and the RSD was 0.73% (n=5). This result was accurate and reproducible. Conclusion The formulation and preparation of FU FANG QIN KUN Cream are reasonable and its quality can be well controlled.
