Effect of Tongxinluo capsule on the plasma C-reactive protein and endothelin-1 in acute coronary syndrome patients
- VernacularTitle:通心络对急性冠状动脉综合征患者血浆C-反应蛋白和内皮素-1的影响
- Author:
Jiaqiang DENG
;
Guoqiang ZHONG
;
Jinru WEI
;
Ruixing YIN
;
Qi BI
- Publication Type:Journal Article
- Keywords:
Acute coronary syndrome;
Tongxinluo capsule;
C-reactive protein;
Endothelin-1
- From:
Clinical Medicine of China
2008;24(6):538-539
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effect of Tongxinluo on the plasma C-reactive protein(CRP)and endothelin-1(ET-1)in acute coronary syndrome(ACS) patients.Methods 100 patients with ACS were randomly divided into conventional therapy group and treatment group(conventional therapy+Tongxinluo gelatin capsule).The changes of CRP and ET-1 in the first day,7th and 14th day were observed.Results In the treatment group,CRP and ET-1 were significantly decreased in the 7th and 14th day(P＜0.05,P＜0.01),and there was significant decrease only in the 14th day(P＜0.05)in the conventional therapy group.CRP and ET-1 levels in the treatment group were significantly different as compared with conventional thereapy group(P＜0.01).Conclusion Tongxinluo capsule may protect blood vessel endothelium through inhibiting CRP and ET-1 to decrease the inflammatory response of endangium.
