Evaluation of non-invasive ventilation in the treatment of chronic obstructive pulmonary disease complicated with typeⅡ respiratory failure
- VernacularTitle:无创通气治疗慢性阻塞性肺疾病并发Ⅱ型呼吸衰竭的临床研究
- Author:
Zhihua HUANG
;
Xiao LIN
;
Yongxu JIN
;
Biying WANG
- Publication Type:Journal Article
- Keywords:
Chronic obstructive pulmonary disease;
Respiratory failure;
Non-invasive ventilation
- From:
Clinical Medicine of China
2008;24(6):545-547
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical significance of BiPAP mechanical ventilation in the treatment of chronic obstructive pulmonary disease(COPD)with type Ⅱ respiratory failure.Methods A total 56 patients suffering from respiratory failure due to exacerbation of COPD were randomly divided into treatment group (BiPAP plus routine therapy)and control group(routine comprehensive therapy).Blood gases,respiratory rates,heart rates,scores of the activity of accessory respiratory muscles,incubation rate,fatality rate were observed.Results In the treatment group,PO2 greatly increased,PCO2 greatly decreased,pH improved significantly,and respiratory rate,heart rate and scores of the activity of accessory respiratory muscles greatly decreased.The incubation rate and the fatality rate were significantly lower in the treatment group than those in the control group(P＜0.05).Conclusion BiPAP mechanical ventilation plus routine therapy on COPD with type Ⅱ respiratory failure can improve the curative effects,lessen respiratory muscle fatigue,and decrease the need for incubation and fatality rate.
