Hemodynamic changes in patients with symptomatic middle cerebral artery stenosis after stenting: a transcranial Doppler evaluation
- VernacularTitle:支架成形术对大脑中动脉狭窄患者短期血液动力学的影响
- Author:
Guihong WANG
;
Weijian JIANG
;
Yongjun WANG
;
Bin DU
;
Kasing WONG
;
Min JIN
;
Suxiang WANG
;
Xiping GONG
- Publication Type:Journal Article
- Keywords:
Ultrasonography,Doppler,transcranal;
Infarction,middle cerebral artery;
Stents;
Hemodynamic phenomena
- From:
Chinese Journal of Ultrasonography
2008;17(5):426-429
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate short-term hemodynamic changes in selected patients with middle cerebral artery(MCA) stenting by transcranial Doppler sonography(TCD).Methods Stenting was given to 29 cases (31 MCAs) of patients with moderate and severe MCA stenosis if they had recurred symptoms during the standard antiplatelet therapy.TCD was applied to assess the hemodynamic changes in the stenosis segment and stenotic distal segment before stenting, 1 h and 3 d after stenting. Results Angiography showed that the rate of post-procedure residual stenoses of MCA were less than 20%.Compared with the pre-stentinng peak systolic velocity [PSV, (273±77)cm/s], the post-stenting PSV significantly decreased,which was (162±38) cm/s (P＜0.01) at 1 hour and (168±45)cm/s ( P＜0.01)at 3 days, respectively.Three cases (3 MCA) experienced recurrent stenosis-like spectra at stenosis segments 3 d after stenting and brain CT showed that 2 out of 3 cases suffered intracranial hemorrhage,which was potentially induced by hyperperfusion; PSV doubled in the stenotic distal segment in at least 28.6% patients.There was no statistic difference between pre- and post-stenting in the contralateral MCA (P＞0.05).Conclusions Stenting can dramatically improve the hemodynamic compromise of stenosis segments and their distal segments in selected patients with symptomatic MCA stenosis, however, potential hyperperfusion risk might he taken into consideration after MCA stenting.
