Application and development of gene chip in the study of ischemia-reperfusion injury
- VernacularTitle:基因芯片技术在缺血再灌注损伤研究中的应用进展
- Author:
Gang CHEN
;
Jinsong LI
- Publication Type:Journal Article
- Keywords:
gene chip;
gene expression;
ischemia-reperfusion injury
- From:
International Journal of Surgery
2008;35(6):422-425
- CountryChina
- Language:Chinese
-
Abstract:
Ischemia-reperfusion injury is a pathophysiological process caused by a number of gene expression changes,with the development of artery occlusion-reperfusion and surgery involved in vascular,such as thrombolytic therapy,cardiopulmonary bypass heart surgery and organ transplants,etc.it has been more and more important.Gene chip technology provides a powerful means for the systematic study of the mechanisms of incidence and prevention of ischemia-reperfusion injury,for its unique advantage in high throughput,high-efficiency,large-scale research.Since gaining importance in recent years,it has been widely used in various organs and tissues,and has achieved some progress.In this paper,the application of gene chip technology in the incidence and prevention of ischemia-reperfusion injury of various organs and tissues in recent years is given a certain summary.
