Nasal continuous positive airway pressure in the treatment of obstructive sleep apnea/hypopnea syndrome with coronary heart disease
- VernacularTitle:经鼻持续气道正压通气治疗睡眠呼吸暂停低通气综合征合并冠心病临床研究
- Author:
Jun ZHAO
;
Furong HAO
;
Heyuan WANG
;
Xiaogang WEI
- Publication Type:Journal Article
- Keywords:
Obstructive sleep apnea/hypopnea syndrome;
Coronary heart disease;
Continuous positive airway oressure
- From:
Clinical Medicine of China
2008;24(6):519-521
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect and mechanism of nasal continuous positive airway pressure(nCPAP)in the treatment of obstructive sleep apnea/hypopnea syndrome(OSAHS)with coronary heart disease.Methods 126 OSAHS patients with coronary heart disease were randomly divided into two groups.The treatment group was treated by nCPAP on the basis of former medicine but the control group was treated by former methods.Three months later,polysomnography(PSG)and the holter ECG examination were conducted.Results After three months,the nocturnal myocardial ischemia episodes decreased significantly in both groups(55.6%and 6.35%,P＜0.01).Conclusion nCPAP may abolish sleep apnea and hypopnea,correct hypoxemia,reduce the nocturnal mean heart rate and systolic blood pressure,and improve myocardial ischemia episodes,so to reduce the incidence of cardiac end-point events.
