The clinical characteristics and surgical treatment of hepatic angiomyolipoma
- VernacularTitle:肝血管平滑肌脂肪瘤的外科治疗
- Author:
Xu CHE
;
Yongfu SHAO
;
Yi SHAN
;
Jianqing CAI
;
Chengfeng WANG
;
Dongbing ZHAO
;
Ping ZHAO
- Publication Type:Journal Article
- Keywords:
Liver neoplasms;
Muscle,smooth,vascular;
Diagnosis;
Surgical procedures,operative
- From:
Chinese Journal of General Surgery
2008;23(5):321-323
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical presentation,pathologic features,diagnosis and treatment of hepatic angiomyohponm(HAML).Methods Retrospective analysis was made on 22 HAML cases in terms of clinical finding,images,pathologic examination and surgical treatment.Results Of the 22 patients,6 were male and 16 were female.The average age was 48.2 years.Seventeen patients had no clinical symptoms.None had the history of hepatitis virus infection.None of them was complicated with renal AML.None had tlle history of taking oral contraceptives in the sixteen female patients.Serum AFP、CEA、CA19-9、CA242 levels were all within normal limits.The correct diagnostic rate of BUS.CT and MRI was 2l%(4/19)、23.5%(4/17)and 25%(2/8),respectively.All tumorts were single nodule with a diameter of 4～17 cm,without complete capsula.All these 22 patients underwent tumor resection,including partial liver resection in 17 patients,left hemihepatectomy in 5.One patient died of postoperative complication,one patient suffered from temporary bile leak.The HMB45 positive rate by immunohistochemical method was 100%.Extramedullary hemopoiesis was found in 4 patients.Follow up of 6 months to 17 years in 91%(20/22)patients found no tumor recurrence. Conclusions HAML had no specifiC symptoms.The preoperative imaging diagnosis is difficult.Surgical resection is the therapy of choice for HAML.
