Observation on the therapeutic Effects of Hepatic Fibrosis of Rats with Salvia Miltiorrhiza
- VernacularTitle:丹参治疗大鼠肝纤维化的效果观察
- Author:
Xiaoyan ZHANG
;
Jianchang SHU
;
Yajun HE
;
Guorong YE
;
Xia LV
- Publication Type:Journal Article
- Keywords:
Salvia mUtiorrhiza;
Hepatic fibrosis;
Treatment
- From:
International Journal of Traditional Chinese Medicine
2008;30(3):172-173
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate therapeutic effects of Salvia miltiorrhiza on hepatic fibrosis of rats induced by carbon tewachloridean. Methods Rat models of hepatic fibrosis were founded by intraperitoneal injection of carbon tetrachloride. Salvia miltiorrhiza were given to these rats. Normal group and control group were set for comparison at the same time. Serum levels of ALT, AST, HA, LN, and PC-Ⅲ were detected; HE and Masson staining were conducted in hepatic tissues to observe pathological variations. Results Salvia miltiorrhiza could decrease serum levels of ALT, AST, HA, LN,PC-Ⅲ obviously (P ＜0.01), compared with the control group; Salvia miltiorrhiza could obviously improve pathological variations compared with the control group. Conclusion Salvia miltiorrhiza has therapeutic effect on hepatic fibrosis of rats
