STUDY ON AFFINITY OF ANTI-HBc IN VIRAL HEPATITIS B PATIENTS AND ASYMPTOMATIC HBsAg CARRIERS
- VernacularTitle:乙型肝炎患者及无症状HBsAg携带者血清中核心抗体亲和力的研究
- Author:
Yumei WEN
- Publication Type:Journal Article
- Keywords:
Affinity of anti-HBc chronic hepatitis B asymptomatic carrier pathogenesis of hepatitis
- From:
Chinese Journal of Infectious Diseases
1988;6(3):129-132
- CountryChina
- Language:Chinese
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Abstract:
An assay for the affinity of serum anti-HBc in chronic hepatitis B patients and asymptomatic HBsAg carriers by 125I,22Na double isotope radioimmunoassay is described.In 7 asymmptomatic HBsAg carriers and 9 chronic hepatitis B patients.the affinity of anti-HBc was 3.25±2.13×106L/Mole in the former,whereas 0.75±0.56×106L/Mole in the latter.The titers of anti-HBc did not correlate to the affinity of anti-HBc and its possib]e role in the pathogenesis of hepatitis B is discussed.
