Research of radionuclide brain blood perfusion imaging toward the clinical diagnosis of in tractable paroxysmal epilepsy
- VernacularTitle:脑血流灌注显像对难治性发作性癫痫诊断的研究
- Author:
Xiaodong LI
;
Rong XUE
;
Xuejun LIU
;
Zuncheng ZHANG
;
Hua DONG
;
Honggang ZHAO
;
Yongtao GUO
- Publication Type:Journal Article
- Keywords:
Radionuclide imaging;
Epilepsy,intractable;
Tomography,emission-computed;
Radiosurgery
- From:
Chinese Journal of Postgraduates of Medicine
2008;31(16):7-10
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical diagnosis value of 99mTc-single photon emission computed tomography(SPECT)brain blood perfusion imaging in intractable paroxysmal epilepsy and analyse the imaging character.Methods Two hundred and thirty-eight intractable paroxysmal epilepsy patients performed99mTc-SPECT,MRI,CT,and electroencephalogram(EEG).The results of examinations were ana lyzed and compared.Results The positive rate of epileptic focus in brain SPECT blood perfusion imaging in the generalized tonic-clonic seizure,absence seizure,partial seizure and complex partial seizure were 85.7%,95.7%,89.8%and 90.9%,the positive rate were much higher than those in other methods(P＜0.01).The 23 patients with SPECT focus were carried on a-γ-knife treatment with follow-up for more than one year,and the efficient rate was 78.26%.Conclusions The detection sentivity of SPECT is distinctively higher than that in others.SPECT has an important clinical value to define target region of the stereotaxic radio surgery.
