Research advancement of mouse mammary stem cell
- VernacularTitle:鼠乳腺干细胞研究进展
- Author:
Xiaowei DOU
;
Rui LIU
- Publication Type:Journal Article
- Keywords:
Stem cells;
Mammary glands,animal
- From:
Journal of International Oncology
2008;35(5):323-326
- CountryChina
- Language:Chinese
-
Abstract:
Mammary stem cell is the subpopulation in mamnlary gland,capable of self-renewal and dif-ferentiating into ductal,alveolar and myoepithelial cells.Recently,several laboratories have employed various methods identifying mammary stem cells,including Sca-1,Hoechst dye efflux,CD24,CD3 1-CIM5-Terl19- CD24+CD29hi and so on.which offer a useful tool to elucidate the mechanism of mammary slem cell self-renew- al and design more effective therapies of mammary cancer.