Summary of the nation-wide autoantibodies test quality survey in 2006
- VernacularTitle:2006年全国自身抗体检测质量控制总结
- Author:
Feng HUANG
;
Xianzi CONG
;
Xiaofeng LI
;
Jianglin ZHANG
;
Yuzhen DING
- Publication Type:Journal Article
- Keywords:
Autoantibodies;
Immunologic tests;
Quality control
- From:
Chinese Journal of Rheumatology
2008;12(6):382-385
- CountryChina
- Language:Chinese
-
Abstract:
objeetive To consecutively understand the current national clinical testing quality and enforce quality-control of auto-antibody detection.Methods Hospitals or departments were recruited by letters or telephone communications:The autoantibodies examined for quality control survey included anti-nuclear antibodies (ANA),anti-double-stranded DNA (A-dsDNA)antibody,anti-extractable nuclear antigens(A-ENA)antobodies,anti-mitochondria antibody(AMA)/anti-smooth muscle antibody(ASMA),and anti-CCP antibody.Each autoantibody was tested in 3 samples, and altogether 15 samples in total for testing.Sample designation and testing results data analysis were double-blinded.Results Fifltv-five hospitals/departments participated in this survey.The accuracy rates for this survey were 92%,89%,96%,72%respectively for ANA,A-dsDNA,AMA/ASMA,and anti-CCP.Anti-ENAs were further divided into anti-RNP,Sm,SSA,SSB and Scl-70 subgroups,and the accuracy rates were 98%,89%,92%,75%and 77% respectively.Conelusion Compared to the previous 3 national surveys.accuracy rates in our country's autoantibody testing is increaseing steadly with more testing items included each year.This indicats that the quality of auto-antibody testing is improving across the country.
