Changes of cardiac rhythms in a swine model of adult asphyxial cardiac arrest
- VernacularTitle:窒息性心跳骤停家猪心脏节律变化
- Author:
Ying SHEN
;
Tangwei LIU
;
Menghua CHEN
;
Jingyu LU
;
Junhui ZHENG
;
Jinlong HE
;
Xianwei ZHANG
- Publication Type:Journal Article
- Keywords:
Cardiac arrest;
Asphyxia;
Cardiac rhythms;
Pig
- From:
Chinese Journal of Emergency Medicine
2008;17(6):614-617
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the changes of cardiac rhythms in a swine model of adult asphyxia! cardiac arrest. Method Sixteen Pigs were aphyxiated by endotracheal tube clamping until 8 min after loss of aortic pulsations. Resuscitation was then provided and swinds were assigned to received 0.045 mg/kg epinephrine intravenously after 3 min of basic life support. The animals with restoration of spontaneous circulation within 20 min from CPR were defined as successfully resuscitated, while the rest were identified as unresuscitation. Electrocardiogram ( EGG) were monitored from the start of asphyxia to the start of the CPR. Results When loss of pulsations occurred, 2 of 16 animals had ventricular fibrillation; 10 pigs exhibited pulseless electrical activity, and 4 pigs had asystole. During the 8 min after the loss of aortic pulsations, pulseless electrical activity converted to VF in 7 pigs. Immidiatedly prior to resuscitation, VF occurred in 9 pigs, asystole in 4 pigs, and PEA in 3 pigs. Conclusions Most of animals in this swine model of asphyxial cardiac arrest presented PEA, but most of them converted to VF especially late in the asphyxial process.
