Role of autophagy in carinogenesis and tumor therapy
- VernacularTitle:自体吞噬在肿瘤发展中的作用及其与肿瘤治疗
- Author:
Kai JIANG
- Publication Type:Journal Article
- Keywords:
Autophagy;
Neoplasms;
Therapy
- From:
Journal of International Oncology
2008;35(5):348-351
- CountryChina
- Language:Chinese
-
Abstract:
Autophagy is a kind of ubiquitous physiological mechanism in normal and abnormal cells.Autophagy plays a key role in protein equilibrium and cleaning impaired organelle to maintain homeostasis in cells.It plays different roles at different stages of carcinogenesis by promoting tumor development or inhibiting tumor growth.It has potential applications for tumor therapy by up-regulating or down-regulating the level of au-tophagy in tumor cells.
