Risk factors and pathogenic analysis in the newborn infants with ventilator-associated pneumonia
- VernacularTitle:新生儿呼吸机相关肺炎危险因素和病原学分析
- Author:
Chao LI
- Publication Type:Journal Article
- Keywords:
Newborn;
Ventilator-associated pneumonia;
Risk factors
- From:
Chinese Pediatric Emergency Medicine
2008;15(3):247-249
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the risk factors and microbial causes related to the pathogenesis of ventilator-associated pneumonia(VAP).Methods Totaly 138 intubated newborn infants for longer than 48 hours in Ningbo Women and Children's Hospital were studied,who were divided into VAP group (56 cases)and non VAP group(82 cases).Microbial causes of VAP were analyzed.Results Malnutrition,repeated tracheal intubation,repeated endotracheal suctioning,indwelling tube,posture,hyaline membrane disease,gestational age,birth weight,duration of intubation,duration of hospitalization were independent risk factors for ventilator-associated pneumonia(P<0.05).Klebsiella pneumoniae,pseudomonas aeruginosa,acinetobacter species and enterobacter cloacae were the main pathogenic bacteria of VAP.Conclusion Shortening of mechanical ventilation duration,avoiding repeated tracheal intubation and indwelling tube usage,semi-fowler positioning can lower the incidence of VAP.Pathogenic bacteria control is essential for VAP.
