Current study of concurrent chemoradiotherapy of squamous cell cancers of head and neck
- VernacularTitle:头颈部鳞癌同步放化疗研究现状
- Author:
Qiuzi ZHONG
- Publication Type:Journal Article
- Keywords:
Head and neck neoplasms;
Radiotherapy;
Drug therapy,combination
- From:
Journal of International Oncology
2008;35(5):358-361
- CountryChina
- Language:Chinese
-
Abstract:
Concurrent chemoradiotherapy (CCRT) is one of the main treating schemes to the locally advanced squamous cell cancers of the head and neck. It has more advantages than the conventional fractionated radiotherapv.Ahhough the side effects may increase,it can be tolerated with the adjuvant treatments.Cisplatin and 5-fluorouracil are taken as the main drugs.Induction chemotherapy followed by CCRT can improve the lo-cal control rate.decrease the distant metastasis rate and obviously increase the survival rate. Intensity modula-ted radiation therapy is recommended.While selecting an appropriate fractionated dose,concomitant boost and aceelerated hyperfraction radiotherapy can obtain a better effect.
