Effects of short-term insulin pump intensive treatment on tumor necrosis factor-α and interleukin-6 in new type 2 diabetic patients
- VernacularTitle:短期胰岛素泵强化治疗对初诊2型糖尿病患者血清肿瘤坏死因子α白细胞介素6水平的影响
- Author:
Xiaofeng LV
;
Kun FANG
- Publication Type:Journal Article
- Keywords:
Tumor necrosis factor-alpha;
Diabetes mellims,type 2
- From:
Chinese Journal of General Practitioners
2008;7(5):338-339
- CountryChina
- Language:Chinese
-
Abstract:
Sixty three new type 2 diabetes(T2DM)mellitus were treated with insulin pump for 2 weeks.Free insulins,fasting plasma slucose,tumor necrosis factor-α(TNF-α)and interleukin(IL)-6 level and other parameters were measured before and after insulin treatment.HOMA-insulin resistance (HOMA-IR)and β-cell function(HOMA-β)were compared.After 2 weeks insulin intensive treatment, TNF-α and IL-6 level were significant lower(P<0.01).HOMA-IR and HOMA.B were signifiant improved (P<0.01).TNF-α and IL-6 levels were positively associated with tlle body mess index and HOMA.IR (P<0.01).TNF-α,IL-6 and HOMA-IR could be significanly improved by short-term insulin pump intensive treatment in new T2DM patients with severe hyperglycemia.
