Adaptive responses on chromosome aberration and DNA breakage of peripheral lymphocytes from workers exposed to thorium and rare earth mixed dust in Baotou Steel Plant
- VernacularTitle:包钢选矿厂含钍粉尘作业工人外周血淋巴细胞适应性反应的研究
- Author:
Qingjie LIU
;
Jiangbin FENG
;
Xue LU
;
Deqing CHEN
;
Yufei LIU
;
Keju XIA
;
Huimin LV
;
Xu SU
- Publication Type:Journal Article
- Keywords:
Thorium and rare earth mixed dust;
Chromosome aberration;
Single cell gel electrophoresis;
Adaptive response
- From:
Chinese Journal of Radiological Medicine and Protection
2008;28(3):235-238
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore if the occupational exposure to low dose thorium could induce adaptive response in peripheral lymphocytes.Methods 40 individuals.who exposed to thorium and rare earth mixed dust(exposure group) or control in Baotou Steel Plant, were selected, and chromosome aberrations were analyzed.Then the peripheral blood samples were irradiated in vitro with 2 Gy60Co γ-rays,and unstable chromosome aberration or DNA stand breakage analysis using single cell gel electrophoresis was performed. Results The dicentrics before 2 Gy exposure in exposure group was higher than that in control(P>0.05). But the dicentries after 2 Gy exposure in exposure group was lower than that in control,but not significantly (P>0.05).The tricentrics in exposure group was significantly lower than that in control(U=3.1622, 0.0ol
