The influence of curative effect and cellular immune function in patients with recurrent genital herpes by two methods
- VernacularTitle:两种方法治疗复发性生殖器疱疹疗效及对细胞免疫功能的影响
- Author:
Yonghui LAI
- Publication Type:Journal Article
- Keywords:
Herpes;
Genitalis;
T-lymphocytos;
helper-inducer;
Valaciclovir;
Mycobacterium phle
- From:
Chinese Journal of Primary Medicine and Pharmacy
2008;15(5):734-735
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the influence of the treatment and T-cell subsets in patients with recurrent genital herpes (RGH) by two treatment methods. Methods 64 cases of RGH patients were randomly divided int0 2 groups: 32 patients in the unite treatment group, the control group of 32 patients. Control group oral valaciclovir. The unite treatment group of oral valaciclovir tablets, in addition, also accepted mycobacterium phle injection treatment. All the patients before and after treatment were analyzed by flow cytometry using T-cell subsets. Results In the unite treatment group after treatment RGH relapse frequency [(1.01±0.79)] than that of the control group [(2.53±0.93)] was significantly decreased (P<0.001). In the unite treatment group after treatment CD+4 T cells and CDCD+4/CDCD+8 ratio than the control group were significantly increased (P<0.05), CD+8 cells compared with the control group was significantly decreased (P<0.05). Conclusion The cellular immunity is abnormal in RGH patients and it plays an important role in pathogenesis of RGH. Mycobacterium phle may enhance cellular immunity of the patients and these patients treated with it showed some better effects.
