Low frequency repetitive transcranial magnetic stimulation in the diagnosis and treatment of cranial dystonia
- VernacularTitle:应用低频重复经颅磁刺激治疗头颈部肌张力障碍
- Author:
Ningjiang LIU
;
Benshu ZHANG
;
Bingdi XIE
;
Huaying TAO
;
Linyang CUI
- Publication Type:Journal Article
- Keywords:
Torticollis;
Magnetics;
Treatment outcome
- From:
Chinese Journal of Neurology
2008;41(6):389-392
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the therapeutic effects of low frequency repetitive transcranial magnetic stimulation(rTMS)in cranial dystonia.Methods Twenty cranial dystoina patients were treated with low frequency rTMS.Their motor threshold,cortical silent period(CSP)were evaluated before and after the rTMS and after 1,2,6 months as well as the spares and Toronto Western Spasmodic Torticollis Rating Scale(TWSTRS)to evaluate the effects of rTMS in the treatment of cranial dvstonia.Results The patients scored(23.5±14.0)significantly lower after l and 2 months(17.6 ±14.3,18.5±14.2,t=2.632,2.149.both P<0.05).But there was an increasing tendeney of the score after 2 months.The 2-month efficient rate of low-frequency rTMS Was 60%(12/20),yet the long-term effect of rTMS was still to be studied.There was a very significant improvment of relaxed(46.5%±7.3%vs49.9%±9.2%,t=-3.235.P<0.05)and active threshold(40.2%±5.9%/)5 43.9%±8.8%,t=-2.339,P<0.05),prolongation of CSP((96.1±24.5)ms vs(121.6±27.7)ms,t=-7.223,P=0.000).Conclusion The low frequency rTMS is efficient to relieve the clinical symptoms of cranial dystonia.
