The study of regional macrophage immune response on ultrasonically guided microwave coagulation therapy for primary hepatic carcinoma
- VernacularTitle:经皮微波凝固治疗原发性肝癌局部巨噬细胞浸润变化的研究
- Author:
Xiujie HAN
;
Baowei DONG
;
Ping LIANG
;
Xiaoling YU
;
Dejiang YU
- Publication Type:Journal Article
- Keywords:
Microwaves;
Liver neoplasms;
Immunity;
Therapy;
Ultrasound
- From:
Chinese Journal of Postgraduates of Medicine
2008;31(18):7-9
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the macrophage immune response after the percutaneous microwave coagulation therapy (PMCT) under the ultrasound guide. Methods Eighty-nine cases of primary hepatic carcinoma patients were treated by PMCT. At the time of the fourth week after PMCT and before PMCT, the patients were given percutaneous biopsy under ultrasound guide. And the samples were stained by immunohistochemical methods. Then the infiltration of macrophage on local treatment areas were compared before and after the treatment. Moreover the function of immunocytes were observed by electronic microscope. Results The infiltration of macrophage increased significantly in post-PMCT as compared with that in pre-PMCT. And there were more protuberance from the macrophage and much more lysosome and endoplasmic reticulum and mitochondrium observed by electronic microscope. Conclusion The local macrophage cellular immunity can be more improved after the primary hepatic carcinoma treated by PMCT.
