Effect of transcatheter bladder arterial chemoembolization on microvessel density change in bladder cancer of the elderly
- VernacularTitle:膀胱动脉化疗栓塞对老年膀胱癌患者肿瘤微血管密度变化的影响
- Author:
Rongjiang WANG
;
Sihai SHAO
;
Qilin SHI
;
Hongxin ZHAO
;
Yinyuan ZHEN
;
Hui LI
;
Xiaonong CHEN
- Publication Type:Journal Article
- Keywords:
Urinary bladder neoplasms;
Embolization,therapeutic;
Neovascularization,Pathologic
- From:
Chinese Journal of Geriatrics
2008;27(6):439-441
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of transcatheter bladder arterial chemoembolization on microvessel density(MVD)change in bladder cancer. Methods The MVD count of bladder cancer tissue of 30 patients before and after chemoembolization were examined by SP immunohistochemical staining.Cancer tissues were examined pathology after chemoembolization.All the cases were followed up for 12 to 36 months(mean 24.6 months),the 3 years survival rate was evaluated clinically. Results MVD counts were 69.8±3.4 and 56.4±3.3 before and after therapy respectively(P<0.05).Cancer tissues were severely damaged ultramicroscopically after interventional chemotherapy.The recurrent rate was 16.67%in 30 cases. Conclusions The chemoembolization could decrease MVD,improve survival rate and reduce the recurrence rate.
