Remifentanil for deliberate hypotension in intracranial aneurysm clamp operation
- VernacularTitle:雷米芬太尼控制性降压在颅内动脉瘤夹闭术中的应用
- Author:
Pengju YANG
;
Zhitao WANG
;
Tieli DONG
- Publication Type:Journal Article
- Keywords:
Intracranial aneurysm;
Hypotension,controlled;
Remifentanil
- From:
Chinese Journal of Postgraduates of Medicine
2008;31(17):25-27
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the effects of remifentanfl for delthemte hypotension in intracranial aneurysm clamp operation,evaluating the feasibility and safety.Methods Twenty intracranial aneurysm patients undergoing occlusion surgery were prospectively randomized in to two groups:Group Ⅰ and Group Ⅱ.Group Ⅰ adopted remifentanil for deliberate hypotension and Group Ⅱ adopted sodium nitroprusside.The data were analyzed with SPSS 11.5 for Windows.Results Deliberate hypotension was achieved at the target mean arterial pressure(MAP)for remifentanil and nitroprusside respectively.During deliberate hypotension,HR in Group Ⅰ were lower than that in Group Ⅱ(P<0.01).RPP in Group Ⅰwere lower than that in Group Ⅱ(P<0.01).Blood loss in Group Ⅰ were lower than that in Group Ⅱ(P<0.05).Conclusion For general anesthesia in intracranial aneurysm clamp operation,using remifentanil for deliberate hypotemion is a good choice.
