Assessment of sedative effects by intravenous injection of fentanyl on neonates with mechanical ventilation
- VernacularTitle:静脉滴注芬太尼对机械通气新生儿镇痛的效果评估
- Author:
Yaping SHI
;
Yushuang JIA
;
Chunmiao XU
;
Zhenlang LIN
- Publication Type:Journal Article
- Keywords:
Mechanical ventilation;
Neonate;
Fentanyl;
Pain
- From:
Chinese Journal of Practical Nursing
2008;24(16):18-20
- CountryChina
- Language:Chinese
-
Abstract:
Objective We aimed to assess the sedative effects by intravenous injection of fentanyl on neonates with mechanical ventilation. Methods We divided 142 neonates with mechanical ventilation into the observation group (92 cases) and the control group (50 cases). The observation group received intravenous injection of fentanyl, while the control group was given no sedative medication. The pain and sedation was assessed before ventilation, 1 and 2 hours after ventilation and later every 4 hours by adoption of NPASS evaluation inventory. Results The scores of pain at different time points 2 hours after medication in the observation group were lower than those in the control group, especially 24 hours after medication. The mean airway pressure and oxygen concentration required by the observation group was lower than those of the control group. But no difference was seen in blood oxygen saturation between the two groups. Conclusions Intravenous injection of fentanyl was proper in the application of sedative treatment for neonates with mechanical ventilation. N-PASS inventory could effectively assess the pain and sedation condition and ensure the safe medication.
