Complement Activation by Tobacco Infusion.
- Author:
Myung Ho CHUNG
1
;
Doo Hie KIM
;
Tae Ho CHUNG
Author Information
1. Graduate School of Public Health, Kyungpook National University, Taegu, Korea.
- Publication Type:In Vitro ; Original Article
- MeSH:
Complement Activation*;
Complement Hemolytic Activity Assay;
Complement System Proteins*;
Tobacco Products;
Tobacco*
- From:Korean Journal of Preventive Medicine
1985;18(1):91-98
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The capacity of tobacco infusions of Korean cigarettes to activate the complement pathway was investigated in vitro by hemolytic assay. Complement activity was studied using samples of normal rabbit serum incubated at 37 degrees C with tobacco infusions. In all mixtures containing tobacco infusion A, B, C, D, E, F, G, H and I at a concentration of 0.1 : 1, total hemolytic complement showed a progressive decrease of 55.92%, 48.62%, 42.89%, 49.12%, 42.26%, 52.26%, 71.96%, 60.90%, and 61.14% respectively, after 60min of incubation. This study suggests that all tobacco infusions of Korean cigarettes are activators of complement.
