In vivo high-resolution magnetic resonance imaging in severe intracranial stenosis
- VernacularTitle:重度颅内动脉狭窄活体高分辨磁共振成像初探
- Author:
Xin LOU
;
Weijian JIANG
;
Lin MA
;
Bin DU
;
Ning MA
;
Feng GAO
- Publication Type:Journal Article
- Keywords:
Middle cerebral artery;
Basilar artery;
Arterial occlusive diseases;
Magnetic resonance imaging
- From:
Chinese Journal of Internal Medicine
2008;47(6):478-481
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess the feasibility and clinical value of high-resolution magnetic resonance imaging (HRMRI) in patients with symptomatic severe intracranial stenosis (SSIS).Methods HRMRl wasperformed with a 3.0 T MR scanner on 5 patients with symptomatic middle cerebral(n=3) or basilar (n=2) arterial stenosis of≥70% confirmed bv DSA.Image diagnosis Was made on the basis of HRMRI findings of vessel wall at the stenotic segment by 2 neuroradiologists blinded t0 patient's status.Results Three of the five patients were diagnosed to have advanced intracranial atherosclerosis based on the presence of a complex eccentric atherosclerotic plaque containing a large lipid-rich necrotic core with a heterogeneous post-contrast enhancement and with signs of ruptured fibrous cap.Two other patients were likely to suffer from non-atherosclerotic lesion.HRMRI revealed an iso-signal septum in the arterial lumen attaching to the slighfly thickened arterial wall that was iso-signal with a homogeneous post-contrast enhancement in one patient and an obviously concentrically thickened arterial wall with hypo-intense signal on T1 WI and slightly high signal on T2 WI and PDWI and without any post-contrast enhancement in the remaining patient.Conclusions In vivo HRMRI in patients with SSIS is technically feasible.It provides detailed information of intracranial arterial wall at the stenotic segment.
