Evaluation on the effect of self-treatment in patients with Keshan disease by echocardiography
- VernacularTitle:超声心动图在克山病患者自我治疗疗效中的评价
- Author:
Changjun WU
;
Hong LIU
;
Zhongyu MA
;
Manli XU
;
Hongqi FENG
;
Tong WANG
- Publication Type:Journal Article
- Keywords:
Echocardiography;
Keshan disease;
Self-treatment;
Ventrieular function,left
- From:
Chinese Journal of Ultrasonography
2008;17(6):487-489
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effect of self-treatment and observe the change of heart morphology and function in patients with Keshan disease by echocardiography.Methods The left atrium diameter(LAd),left ventricular end-diastolic diameter(LVEDd),the thickness of interventricular septum in end diastolic(IVSTd),the thickness of left ventricular posterior wall in end-diastolic(LVPWTd),the left ventricular mass(LVM),the left ventricular mass index(LVMI),the relative wall thickness(RWT),the left ventricular ejection fraction(LVEF)and the mitral valve flow E/A ratio(E/A)were measured before the self treatment by echocardiography,and also measured on the 3rd month and 6th month after self-treatment with the same method,and observed the change of the parameters above.Results The LAd,LVEDd,IVSTd,LVPWTd,LVM,LVMI and RWT decreased on the 3rd month after self-treatment compared with prior self-treatment,and decreased on the 6th month further.There was significant difference between the prior self-treatment and post self-treatment(P＜0.05).The mitral valve flow E/A ratio and LVEF increased on the post self-treatment compared with the prior self-treatment slightly,but there was no statistical difference(P＞0.05).Conclusions Left ventricular hypertrophy and remodeling in patients with Keshan disease were prevented and reversed,and the cardiac function were improved after the self-treatment.Echocardiography can be used to evaluate the effect of self-treatment on patients with Keshan disease and can provide direction for clinical treatment.
